SCHEDULE 14A
                                 (Rule 14a-101)
                     INFORMATION REQUIRED IN PROXY STATEMENT
                            SCHEDULE 14A INFORMATION
                Proxy Statement pursuant to Section 14(a) of the
                         Securities Exchange Act of 1934

Filed by the Registrant |X|
Filed by a Party other than the Registrant |_|

Check the appropriate box:

|_|   Preliminary Proxy Statement
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      14a-6(e)(2))
|X|   Definitive Proxy Statement
|_|   Definitive Additional Materials
|_|   Soliciting Material Under Rule 14a-12

                             SIGA TECHNOLOGIES, INC.

                (Name of Registrant as Specified in Its Charter)


    ------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

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                             SIGA Technologies, Inc.
                         420 Lexington Avenue, Suite 408
                            New York, New York 10170
                                 (212) 672-9100

November 17, 2006

Dear Stockholder:

      You are cordially  invited to attend the Annual Meeting of Stockholders of
SIGA  Technologies,  Inc.  which  will be held at the  offices  of Kramer  Levin
Naftalis & Frankel LLP, 1177 Avenue of the Americas,  29th Floor,  New York, New
York 10036 at 10:30 a.m. (local time) on Tuesday,  December 19, 2006, and at any
adjournment or  postponement  thereof.  On the following pages you will find the
formal notice of annual meeting and proxy statement.

      To assure that you are represented at the Annual  Meeting,  whether or not
you plan to attend the meeting in person, please read carefully the accompanying
proxy  statement,  which  describes  the  matters to be voted  upon,  and please
complete, date, sign and return the enclosed proxy card promptly.

      I hope that you will attend the  meeting and I look  forward to seeing you
there.

                                                Sincerely,


                                                /s/ Donald G. Drapkin
                                                ---------------------
                                                DONALD G. DRAPKIN
                                                Chairman of the Board



                             SIGA Technologies, Inc.
                         420 Lexington Avenue, Suite 408
                            New York, New York 10170

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                         TO BE HELD ON DECEMBER 19, 2006

      NOTICE IS HEREBY  GIVEN  that the  Annual  Meeting  of  Stockholders  (the
"Annual Meeting") of SIGA Technologies,  Inc., a Delaware corporation  ("SIGA"),
will be held on Tuesday,  December 19, 2006, at 10:30 a.m.  (local time), at the
offices of Kramer  Levin  Naftalis & Frankel LLP,  1177 Avenue of the  Americas,
29th Floor, New York, New York 10036, and at any adjournment.

      At the Annual Meeting,  SIGA's stockholders will be voting on proposals to
do the following:

      1.    To elect ten directors to the Board of Directors of SIGA;

      2.    To  ratify  the  appointment  of  PricewaterhouseCoopers  LLP as the
            independent registered public accounting firm of SIGA for the fiscal
            year ending December 31, 2006; and

      3.    To  transact  such other  business as may  properly  come before the
            Annual Meeting or at any adjournment or postponement thereof.

      Stockholders  of record at the close of  business  on November 6, 2006 are
entitled to notice of, and to vote at, the Annual Meeting or any  adjournment or
postponement  thereof.  A list of such  stockholders  will be  available  at the
Annual Meeting and for any purpose related to the Annual Meeting, during the ten
days prior to the Annual Meeting,  at SIGA's office,  during  ordinary  business
hours.

      All  stockholders are cordially  invited to attend the Annual Meeting.  If
you do not expect to be present at the Annual Meeting, you are requested to fill
in,  date and sign the  enclosed  proxy  and mail it  promptly  in the  enclosed
envelope to make sure that your shares are represented at the Annual Meeting. In
the event you  decide to attend the Annual  Meeting in person,  you may,  if you
desire, revoke your proxy and vote your shares in person.

                             YOUR VOTE IS IMPORTANT

   IF YOU ARE UNABLE TO BE PRESENT PERSONALLY, PLEASE MARK, SIGN AND DATE THE
 ENCLOSED PROXY, WHICH IS BEING SOLICITED BY THE BOARD OF DIRECTORS, AND RETURN
                      IT PROMPTLY IN THE ENCLOSED ENVELOPE.

                                        By Order of the Board of Directors,


                                        /s/ Thomas N. Konatich
                                        ----------------------
                                        Thomas N. Konatich
                                        Secretary

New York, New York
November 17, 2006



                             SIGA Technologies, Inc.
                         420 Lexington Avenue, Suite 408
                            New York, New York 10170

                                 --------------
                                 PROXY STATEMENT
                         ANNUAL MEETING OF STOCKHOLDERS
                                DECEMBER 19, 2006

                                 --------------

      This proxy statement is furnished to  stockholders  of SIGA  Technologies,
Inc.   ("SIGA")  in  connection  with  the  solicitation  of  proxies,   in  the
accompanying  form, by the Board of Directors of SIGA (the "Board of Directors")
for use in voting at the Annual Meeting of Stockholders  (the "Annual  Meeting")
to be held at the offices of Kramer Levin Naftalis & Frankel LLP, 1177 Avenue of
the Americas,  29th Floor,  New York, New York 10036,  on Tuesday,  December 19,
2006, at 10:30 a.m., and at any adjournment or postponement thereof.

      This proxy statement,  and the accompanying form of proxy, are first being
mailed to stockholders on or about November 27, 2006.

                    VOTING RIGHTS AND SOLICITATION OF PROXIES

Purpose of the Annual Meeting

      The  specific  proposals  to be  considered  and acted  upon at the Annual
Meeting  are  summarized  in  the  accompanying  Notice  of  Annual  Meeting  of
Stockholders. Each proposal is described in more detail in this proxy statement.

Record Date and Outstanding Shares

      The Board of Directors has fixed the close of business on November 6, 2006
as the record date (the "Record  Date") for the  determination  of  stockholders
entitled to notice of, and to vote at, the Annual Meeting.  Only stockholders of
record at the close of  business  on the Record Date will be entitled to vote at
the Annual Meeting or any and all adjournments or postponements  thereof.  As of
the Record Date,  SIGA had issued and  outstanding  31,796,454  shares of common
stock, par value $.0001 per share ("Common Stock").

Voting at the Annual Meeting

      Each share of Common Stock outstanding on the Record Date will be entitled
to one vote on each matter submitted to a vote of the  stockholders.  Cumulative
voting by stockholders is not permitted.

      The presence,  in person or by proxy,  of the holders of a majority of the
votes  entitled  to be cast by the  stockholders  entitled to vote at the Annual
Meeting is necessary to constitute a quorum.  Abstentions and broker "non-votes"
are  counted as present  and  entitled to vote for  purposes  of  determining  a
quorum.  A  broker  "non-vote"  occurs  when  a  nominee  holding  shares  for a
beneficial owner does not vote on a particular proposal because the nominee does
not  have  discretionary  voting  power  for  that  particular  item and has not
received instructions from the beneficial owner.

      For the election of directors,  a plurality of the votes cast is required.
Abstentions  and broker  "non-votes"  are not  considered for the purpose of the
election of directors.

      For the ratification of the appointment of  PricewaterhouseCoopers  LLP as
the independent  registered  public  accounting firm of SIGA for the fiscal year
ending December 31, 2006, the affirmative  vote of a majority of the total votes
cast on such  proposal in person or by proxy at the Annual  Meeting is required.
Abstentions and broker  "non-votes" for such proposal are not considered to have
been voted on the proposal.


                                       1


Revocability and Voting of Proxies

      Any person signing a proxy in the form  accompanying  this proxy statement
has the power to revoke it prior to the Annual  Meeting or at the Annual Meeting
prior to the vote  pursuant  to the proxy.  A proxy may be revoked by any of the
following methods:

o     by writing a letter  delivered to Thomas N.  Konatich,  Secretary of SIGA,
      stating that the proxy is revoked;

o     by submitting another proxy with a later date; or

o     by attending the Annual Meeting and voting in person.

      Please note, however, that if a stockholder's shares are held of record by
a  broker,  bank or other  nominee  and that  stockholder  wishes to vote at the
Annual Meeting,  the stockholder  must bring to the Annual Meeting a letter from
the broker,  bank or other  nominee  confirming  that  stockholder's  beneficial
ownership of the shares.

      Unless we receive  specific  instructions  to the  contrary or unless such
proxy is revoked,  shares  represented  by each properly  executed proxy will be
voted:  (i) FOR the election of each of SIGA's nominees as a director;  (ii) FOR
the  ratification  of  the  appointment  of  PricewaterhouseCoopers  LLP  as the
independent registered public accounting firm of SIGA for the fiscal year ending
December 31, 2006; and (iii) with respect to any other matters that may properly
come before the Annual  Meeting,  at the discretion of the proxy  holders.  SIGA
does not  presently  anticipate  that any other  business  will be presented for
action at the Annual Meeting.

Solicitation

      SIGA will pay the costs relating to this proxy  statement,  the proxy card
and the Annual  Meeting.  SIGA may reimburse  brokerage  firms and other persons
representing  beneficial  owners of  shares  for their  expenses  in  forwarding
solicitation  material to  beneficial  owners.  Directors,  officers and regular
employees may also solicit proxies by telephone,  facsimile or other means or in
person. They will not receive any additional payments for the solicitation.


                                       2


                                 PROPOSAL NO. 1

                              ELECTION OF DIRECTORS

      Ten directors are to be elected at the Annual Meeting to hold office until
the next Annual Meeting of  Stockholders  and until their  successors  have been
duly elected and qualified.  Unless otherwise instructed, the proxy holders will
vote the proxies  received by them FOR the election of the ten persons  named in
the table  below as  directors  of SIGA.  Proxies  cannot be voted for a greater
number of persons  than the nominees  named.  In the event that any of the below
listed  nominees for director  should  become  unavailable  for election for any
presently  unforeseen  reason,  the persons named in the accompanying proxy form
have the right to use their discretion to vote for a substitute.

      THE BOARD OF DIRECTORS  RECOMMENDS  THAT THE  STOCKHOLDERS  VOTE "FOR" THE
ELECTION  (ITEM 1 OF THE ENCLOSED  PROXY CARD) OF MR.  DRAPKIN,  MR. ANTAL,  MR.
CONSTANCE,  DR. MJALLI,  DR. OZ, DR. ROSE, MR. SAVAS, MS. SLOTKIN AND DR. WEINER
AS DIRECTORS.

Director Nominee Information

The  following  table  sets  forth  biographical  information  of each  director
nominee,  including their ages, data on their business backgrounds and the names
of public  companies  and other  selected  entities for which they also serve as
directors:

         Name                                   Age      Position
         ----                                   ---      --------
         Donald G. Drapkin*                     58       Chairman of the Board
         James J. Antal*                        55       Director
         Thomas E. Constance*                   69       Director
         Adnan M. Mjalli, Ph.D.                 42       Director
         Mehmet C. Oz, M.D. *                   44       Director
         Eric A. Rose, M.D. *                   54       Director
         Paul G. Savas*                         43       Director
         Judy S. Slotkin*                       53       Director
         Michael A.  Weiner, M.D. *             60       Director
         Scott M. Hammer, M.D. *                59       Director

      *     Determined by the Board of Directors to be  independent  pursuant to
            Rule 4200 of the NASD Marketplace Rules.

      Donald G.  Drapkin  has served as  Chairman of the Board and a director of
SIGA since April 19, 2001.  Mr. Drapkin has been Vice Chairman and a director of
MacAndrews  & Forbes  Holdings  Inc. and various of its  affiliates  since 1987.
Prior to joining  MacAndrews & Forbes, Mr. Drapkin was a partner in the law firm
of  Skadden,  Arps,  Slate,  Meagher & Flom LLP for more than  five  years.  Mr.
Drapkin is also a director  of the  following  corporations  which file  reports
pursuant to the  Securities  Exchange  Act of 1934:  Anthracite  Capital,  Inc.,
Playboy Enterprises, Inc., Revlon Consumer Products Corporation, Revlon Inc. and
Nephros,  Inc. Mr. Drapkin is also a director of PharmaCore,  Inc. and TransTech
Pharma, Inc.

      James J. Antal has served as a director of SIGA since  November  2004. Mr.
Antal has been an active  consultant and founding  investor in several  Southern
California based emerging  companies since his retirement from Experian in 2002.
He has served as Chief  Financial  Advisor  to Black  Mountain  Gold  Coffee Co.
(2003-2005),  and as Chief  Financial  Officer of Pathway  Data,  Inc.  (2005 to
present).  Mr. Antal joined the Board of Directors and serves as the Chairman of
the audit committee for  ClevelandBioLabs,  effective upon the completion of the
CBLI IPO,  which  occurred  in July,  2006.  Mr.  Antal was the Chief  Financial
Officer and Chief  Investment  Officer  from 1996 to 2002 for  Experian,  a $1.6
billion global information services subsidiary of UK-based GUS plc. Prior to the
GUS  acquisition  of  Experian  (the  former TRW Inc.  Information  Systems  and
Services  businesses),  Mr. Antal held various  finance  positions with TRW from
1978 to 1996, including Senior VP of Finance for TRW Information


                                       3


Systems and Services and TRW Inc. Corporate Director of Financial  Reporting and
Accounting. He earned his undergraduate degree in accounting from The Ohio State
University in 1973, and became a certified public  accountant (Ohio) in 1974. He
engaged in active practice as a CPA with Ernst & Ernst until 1978. Mr. Antal has
served as a director of First American Real Estate Solutions,  an Experian joint
venture with First American Financial Corp.

      Thomas E. Constance has served as a director of SIGA since April 19, 2001.
Mr.  Constance is Chairman and, since 1994, a partner of Kramer Levin Naftalis &
Frankel LLP, a law firm in New York City. Mr.  Constance  serves as a Trustee of
the M.D.  Sass  Foundation  and St.  Vincent's  Services.  He also serves on the
Advisory Board of Directors of Barington Capital, L.P.

      Adnan M.  Mjalli,  Ph.D.  has served as a director  of SIGA since  January
2004. Dr. Mjalli founded TransTech Pharma, Inc., a privately held drug discovery
company  in High  Point,  North  Carolina,  in 1999 and has since  served as its
President and Chief Executive  Officer.  He also serves as Chairman of the Board
of  PharmaCore,  Inc.  where he  previously  served  as  President  and CEO from
December of 1998 to November  2000.  Dr. Mjalli  obtained his Ph.D. in medicinal
chemistry in 1989 from the University of Exeter,  UK. His postdoctoral  work was
carried out at the University of Rochester.  Prior to founding TransTech Pharma,
he held various  positions of increasing  responsibility  in research and senior
management at several  pharmaceutical  and  biotechnology  companies,  including
Merck & Co., Inc.

      Mehmet C. Oz, M.D.  has served as a director of SIGA since April 19, 2001.
Dr. Oz has been a Cardiac Surgeon at Columbia University  Presbyterian  Hospital
since 1993 and a  Professor  of Surgery  and Vice  Chairman  for  Cardiovascular
Services of the  Department of Surgery there since July 2001. Dr. Oz directs the
following  programs  at New  York  University  Presbyterian  Hospital,  Columbia
University:  the Cardiovascular  Institute,  the complementary medicine program,
the clinical  profusion program and clinical trials of new surgical  technology.
Dr. Oz received his undergraduate  degree from Harvard  University in 1982, and,
in  1986,  he  received  a joint  M.D./M.B.A.  degree  from  the  University  of
Pennsylvania Medical School and the Wharton School of Business.

      Eric A. Rose,  M.D. has served as a director of SIGA since April 19, 2001.
From April 19,  2001 until  June 21,  2001,  Dr.  Rose  served as Interim  Chief
Executive  Officer of SIGA. Dr. Rose is currently  Chairman of the Department of
Surgery and  Surgeon-in-Chief  of the Columbia  Presbyterian  Center of New York
Presbyterian  Hospital,  a position he has held since August 1994. Dr. Rose is a
past President of the International  Society for Heart and Lung Transplantation.
Dr. Rose was recently  appointed as Morris & Rose Milstein  Professor of Surgery
at Columbia  University's  College of  Physicians  and  Surgeons'  Department of
Surgery. Dr. Rose is a director of PharmaCore,  Inc., TransTech Pharma, Inc. and
a former  director of Nexell  Therapeutics  Inc.  (f/k/a  VimRx).  Dr. Rose is a
graduate of both Columbia College and Columbia  University College of Physicians
& Surgeons.

      Paul G. Savas has served as a director  of SIGA since  January  2004.  Mr.
Savas has been an Executive  Vice  President  of Finance at  MacAndrews & Forbes
Holdings,  Inc. and its  affiliates  since May 2006.  Prior to that he served in
various positions at MacAndrews & Forbes and its affiliates, including as Senior
Vice President of Finance from October 2002 until May 2006,  Vice President from
1998 until 2002,  and  Director of Corporate  Finance from 1994 until 1998.  Mr.
Savas is a director  of Rev  Holdings  LLC,  Clarke  American  Corp.,  TransTech
Pharma, Inc. and PharmaCore, Inc.

      Judy S. Slotkin has served as a director of SIGA since  November 2004. Ms.
Slotkin was Co-Head of the Finance  Committee of the Modern  Africa Fund, a $120
million  private  equity fund,  from 1998 until 2003.  Ms.  Slotkin was formerly
Department  Head  in the  Corporate  Finance  Division  of  Citigroup  (Citibank
Investment Bank) where she was responsible for various  businesses and the first
head of the group's  Capital  Markets  Desk.  Prior to that,  Ms.  Slotkin  held
various positions in the Citigroup (Citibank)  commercial bank. Ms. Slotkin is a
director of Nephros,  Inc.  Ms.  Slotkin  received her  undergraduate  degree in
accounting from Fairleigh Dickinson  University in 1976 and in 1980 she received
her MBA in Finance from Fordham University.

      Michael A.  Weiner,  M.D. has served as a director of SIGA since April 19,
2001. Dr. Weiner is the Hettinger Professor of Pediatrics at Columbia University
College of Physicians  and Surgeons  since 1996. Dr. Weiner is also the Director
of  Pediatric  Oncology  at New York  Presbyterian  Hospital.  Dr.  Weiner was a
director of Nexell Therapeutics,  Inc. (f/k/a VimRx) from March 1996 to February
1999. Dr. Weiner is a 1972


                                       4


graduate of the New York State Health Sciences Center at Syracuse and was a post
graduate student at New York University and Johns Hopkins University.

      Dr.  Hammer is the  Harold C. Neu  Professor  of  Medicine,  Professor  of
Epidemiology  and Chief of the Division of  Infectious  Diseases at the Columbia
University  Medical  Center  (CUMC),  a  position  he has held since  1999.  Dr.
Hammer's  major  investigative  interest is the treatment and  prevention of HIV
disease.  He is an investigator in the National  Institutes of Health  sponsored
AIDS Clinical  Trials Group (ACTG),  a multicenter  organization  which performs
clinical  trials  designed to improve the  understanding  and  treatment  of HIV
infection and its complications. As an ACTG investigator, Dr. Hammer chaired the
two largest national trials of antiretroviral  therapy carried out by that group
in the 1990's,  studies which contributed to the current standard of care of HIV
infection.  In  addition  to his  interest  in the  treatment  of  persons  with
established  HIV  infection,  Dr.  Hammer  is an  investigator  in the  National
Institutes of Health  sponsored HIV Vaccine Trials Network (HVTN), a multicenter
organization whose mission is to develop an effective preventive HIV vaccine. He
is Chair of the AIDS Vaccine  Research  Working Group, an advisory  committee to
the  Division of AIDS,  NIAID.  He is a former Chair of the  Antiviral  Products
Advisory  Committee of the Food and Drug  Administration and currently serves on
the Editorial Board of the New England Journal of Medicine.  Dr. Hammer is Chair
of the International  AIDS Society-USA's  Antiretroviral  Guidelines Panel, is a
member of the Governing Council of the International  AIDS Society,  is a member
of the World Health  Organization's  Strategic and Technical  Advisory Committee
for HIV/AIDS,  serves as Co-Chair of the Steering  Committee of the WHO's Global
HIV  Drug  Resistance  Surveillance  Program,  and  continues  in  his  role  as
Guidelines  Development Group Chair of the WHO's  Antiretroviral  Guidelines for
Resource  Limited  Settings.  He has  served  as a member  of the  International
Advisory  Committees  of  the  Swiss  HIV  Cohort  Study,  the  French  National
Association  for AIDS Research and the HIV-NAT  (Netherlands-Australia-Thailand)
Collaborative  Research  Network.  In his  role  as  Chief  of the  Division  of
Infectious Diseases at CUMC, he is dedicated to fellow and faculty growth and to
the development of state-of-the-art  infection surveillance at the institutional
and regional levels to improve and protect the public health.

Meetings of the Board of Directors

      The Board of Directors of SIGA held six meetings during 2005. During 2005,
one  director  attended  fewer than 75% of the  aggregate of the meetings of the
Board of Directors  and  committees  thereof,  upon which such  director  served
during  the  period for which he has been a director  or  committee  member.  In
addition,  2 actions were taken during 2005 by unanimous  written consent of the
directors.

      Those members of the Board of Directors who are  independent as defined by
Rule 4200 of the NASD Marketplace Rules (the  "Independent  Directors") are also
required,  pursuant  to  Rule  4350(c)(2)  of the  NASD  Marketplace  Rules,  to
regularly convene executive  sessions where only such Independent  Directors are
present. Such meetings may be in conjunction with  regularly-scheduled  meetings
of the  Board of  Directors.  Each  member  of the  Board of  Directors  is also
expected to attend the annual meeting of stockholders of SIGA.  Seven members of
the Board of Directors attended SIGA's 2005 annual meeting of stockholders.

Committees of the Board of Directors

      The Board of  Directors  currently  has,  and  appoints  the  members  of,
standing Audit, Compensation and Nominating and Corporate Governance Committees.
Each member of the Audit,  Compensation and Nominating and Corporate  Governance
Committees is an Independent  Director.  Each of these  committees has a written
charter  approved by the Board of the  Directors  in March 2004.  A copy of each
charter  is  posted on  SIGA's  website  at  www.siga.com  under the  "Corporate
Governance" section.

      Audit  Committee.  The  Audit  Committee,   which  currently  consists  of
directors Paul G. Savas,  Judy S. Slotkin and James J. Antal,  held ten meetings
during 2005. The Board of Directors has  determined  that each of the members of
the Audit  Committee  is  "independent"  under the  applicable  laws,  rules and
regulations.  The Company has determined  that Mr. Savas is an "Audit  Committee
financial  expert"  within the  meaning of  Regulation  S-K  promulgated  by the
Securities  and  Exchange  Commission  (the  "SEC").  The  purpose  of the Audit
Committee is to assist the Board of Directors in the  oversight of the integrity
of the financial statements of SIGA, SIGA's compliance with legal and regulatory
matters, the independent registered public accounting firm's qualifications and


                                       5


independence,  and the  performance  of  SIGA's  independent  registered  public
accounting  firm. The primary  responsibilities  of the Audit  Committee are set
forth in its charter,  and include various matters with respect to the oversight
of SIGA's accounting and financial reporting process and audits of the financial
statements of SIGA on behalf of the Board of Directors. The Audit Committee also
selects the independent  registered public accounting firm to conduct the annual
audit of the financial  statements of SIGA;  reviews the proposed  scope of such
audit;  reviews  accounting and financial  controls of SIGA with the independent
registered  public  accounting  firm and our  financial  accounting  staff;  and
reviews and approves  transactions between us and our directors,  officers,  and
their  affiliates.  A copy of the Audit Committee charter is available on SIGA's
website (as described above). Also see "Audit Committee Report."

      Compensation  Committee.  The  Compensation  Committee,   which  currently
consists of directors  Donald G.  Drapkin,  Paul G. Savas and Mehmet C. Oz, held
one meeting during 2005. The Board of Directors has determined  that each of the
members of the Compensation Committee is "independent" within the meaning of the
NASDAQ listing standards. The Compensation Committee functions include reviewing
and  approving  the  compensation  and benefits for SIGA's  executive  officers,
administering  SIGA's  stock  plans and making  recommendations  to the Board of
Directors regarding these matters. A copy of the Compensation  Committee charter
is available on SIGA's website. Also see "Compensation Committee Report."

      Nominating  and  Corporate  Governance   Committee.   The  Nominating  and
Corporate  Governance  Committee (the "Nominating  Committee"),  which currently
consists of directors Judy S. Slotkin, James J. Antal and Michael A. Weiner, was
formed in March 2004 and held three meetings in 2005. The Board of Directors has
determined that each of the members of the Nominating Committee is "independent"
within the meaning of the NASDAQ listing standards.  The Nominating Committee is
responsible  for  searching  for and  recommending  to the  Board  of  Directors
potential nominees for director positions,  making  recommendations to the Board
of Directors  regarding the size and  composition  of the Board of Directors and
its committees,  monitoring the Board of Director's effectiveness and developing
and implementing SIGA's corporate governance  procedures and policies. A copy of
the Nominating and Corporate Governance Committee charter is available on SIGA's
website.

      In  selecting  candidates  for the  Board  of  Directors,  the  Nominating
Committee  begins by  determining  whether the incumbent  directors  whose terms
expire at the  annual  meeting  of  stockholders  desire  and are  qualified  to
continue  their service on the Board of Directors.  SIGA is of the view that the
continuing service of qualified  incumbents promotes stability and continuity in
the board  room,  giving SIGA the benefit of the  familiarity  and insight  into
SIGA's affairs that its directors have  accumulated  during their tenure,  while
contributing  to the Board of Director's  ability to work as a collective  body.
Accordingly,  it is the  policy  of the  Nominating  Committee,  absent  special
circumstances, to nominate qualified incumbent directors who continue to satisfy
the  Nominating  Committee's  criteria for membership on the Board of Directors,
whom  the  Nominating   Committee  believes  will  continue  to  make  important
contributions to the Board of Directors and who consent to stand for re-election
and, if  re-elected,  to continue  their service on the Board of  Directors.  If
there are positions on the Board of Directors for which the Nominating Committee
will not be re-nominating an incumbent director, or if there is a vacancy on the
Board of Directors,  the Nominating  Committee will solicit  recommendations for
nominees from persons whom the  Nominating  Committee  believes are likely to be
familiar with qualified candidates,  including members of the Board of Directors
and management of SIGA. The Nominating  Committee may also engage a professional
search firm to assist in the identification of qualified candidates, but did not
do so in 2005. As to each  recommended  candidate that the Nominating  Committee
believes merits serious consideration,  the Nominating Committee will collect as
much  information,  including  without  limitation,  soliciting views from other
directors  and SIGA's  management  and having one or more  Nominating  Committee
members  interview  each such  candidate,  regarding  each candidate as it deems
necessary or appropriate  in order to make an informed  decision with respect to
such candidate.  Based on all available information and relevant considerations,
the Nominating  Committee will select,  for each  directorship  to be filled,  a
candidate  who,  in the view of the  Nominating  Committee,  is most  suited for
membership  on the  Board of  Directors.  In  making  its  selection,  SIGA will
evaluate  candidates  proposed by  stockholders  under  criteria  similar to the
evaluation  of other  candidates,  except  that  the  Nominating  Committee  may
consider,  as one of the factors in its  evaluation of  stockholder  recommended
nominees, the size and duration of the interest of the recommending  stockholder
or stockholder group in the equity of SIGA. This  consideration may also include
how long the  recommending  stockholder  intends to continue  holding its equity
interest in SIGA.


                                       6


      The  Nominating  Committee has adopted a policy with regard to the minimum
qualifications  that must be met by a Nomination  Committee-recommended  nominee
for a position on SIGA's Board of  Directors,  which policy is described in this
paragraph.  The Nominating  Committee generally requires that all candidates for
the Board of Directors be of high personal integrity and ethical character.  The
Nominating Committee requires that candidates not have any interests that would,
in the view of the Nominating Committee, materially impair his or her ability to
(i) exercise  independent  judgment or (ii)  otherwise  discharge  the fiduciary
duties owed as a director to SIGA and its stockholders.  In addition, candidates
must be able to represent  fairly and equally all  stockholders  of SIGA without
favoring or advancing any particular  stockholder or other constituency of SIGA.
Candidates must have demonstrated achievement in one or more fields of business,
professional,   governmental,  communal,  scientific  or  educational  endeavor.
Candidates  are  expected  to have  sound  judgment  and a general  appreciation
regarding major issues facing public  companies of a size and operational  scope
similar  to  SIGA,  including  contemporary   governance  concerns,   regulatory
obligations of a public issuer,  strategic business  planning,  competition in a
global economy,  and basic concepts of corporate  finance.  Candidates must also
have, and be prepared to devote,  adequate time to the Board and its committees.
It is expected that,  taking into account their other business and  professional
commitments,  including  their  service on the boards of other  companies,  each
candidate  will be available to attend  meetings of the Board and any committees
on  which  the  candidate  will  serve,  as well as  SIGA's  annual  meeting  of
stockholders.  SIGA also  requires  that at least a  majority  of the  directors
serving at any time on the Board are independent,  as defined under the rules of
the NASDAQ  stock  market and that at least three of the  directors  satisfy the
financial  literacy  requirements  required  for service on the Audit  Committee
under the rules of the NASDAQ stock market.

      The  Nominating  Committee  has  adopted  a  policy  with  regard  to  the
consideration of director candidates  recommended by stockholders,  the material
elements  of which  policy  are  described  in this  paragraph.  The  Nominating
Committee will consider recommendations for nomination for director submitted by
holders  of  SIGA's  shares  entitled  to  vote  generally  in the  election  of
directors.   The  Nominating   Committee  will  give   consideration   to  these
recommendations  for positions on the Board where the  Nominating  Committee has
not  determined  to  re-nominate  a  qualified  incumbent  director.  While  the
Nominating  Committee  has not  established  a minimum  number of shares  that a
stockholder  must  own in order  to  present  a  nominating  recommendation  for
consideration, or a minimum length of time during which the stockholder must own
its shares, the Nominating Committee may take into account the size and duration
of a  recommending  stockholder's  ownership  interest in SIGA.  The  Nominating
Committee  may also  consider  whether  the  stockholder  making the  nominating
recommendation   intends  to   maintain  an   ownership   interest  in  SIGA  of
substantially  the  same  size as at its  interest  at the  time of  making  the
recommendation.  The Nominating Committee may refuse to consider recommendations
of nominees  who do not satisfy the  minimum  qualifications  prescribed  by the
Nominating Committee for board candidates.

      The  Nominating  Committee  has  adopted  procedures  to  be  followed  by
stockholders  in  submitting  recommendations  of candidates  for director.  The
procedures  are posted on SIGA's  website at  www.siga.com  under the "Corporate
Governance" section, and described in this paragraph. A stockholder (or group of
stockholders)  wishing  to  submit a  nominating  recommendation  for an  annual
meeting of  stockholders  should try to ensure that it is  received by SIGA,  as
provided herein, not later than 120 calendar days prior to the first anniversary
of the date of the proxy statement for the prior annual meeting of stockholders.
All stockholder nominating  recommendations  should be in writing,  addressed to
"the  Nominating  and  Corporate  Governance  Committee"  care of  SIGA's  Chief
Financial Officer at SIGA's principal headquarters,  420 Lexington Avenue, Suite
408, New York, New York 10170.  Submissions  should be made by mail,  courier or
personal  delivery.  A nominating  recommendation  should be  accompanied by the
following information concerning each recommending stockholder:

o     The name and address,  including  telephone  number,  of the  recommending
      stockholder;

o     The number and class of SIGA's shares owned (beneficially or of record) by
      the  recommending  stockholder  and the time  period for which such shares
      have been held;

o     A statement from the  stockholder as to whether the stockholder has a good
      faith  intention to continue to hold the reported  shares through the date
      of SIGA's next annual meeting of stockholders;

o     Sufficient  information  about the  proposed  nominee  for the  Nominating
      Committee to make an informed decision regarding the qualifications of the
      proposed nominee;


                                       7


o     Any  relationship  between  the  proposed  nominee  and  the  recommending
      stockholder; and

o     Such other information as the Nominating Committee may reasonably request.

The nominating recommendation must be accompanied by the consent of the proposed
nominee  to be  interviewed  by the  Nominating  Committee,  if  the  Nominating
Committee  chooses to do so in its discretion (and the recommending  stockholder
must  furnish the  nominee's  contact  information  for this  purpose),  and, if
nominated and elected, to serve as a director of SIGA.

Compensation Committee Interlocks and Insider Participation

      None.

Code of Ethics

      SIGA has adopted a code of ethics and business conduct that applies to its
officers,  directors and  employees,  including  without  limitation,  our Chief
Executive  Officer,  Chief Financial Officer and Chief Scientific  Officer.  The
Code  of  Ethics  and  Business  Conduct  is  available  on  SIGA's  website  at
www.siga.com under the "Corporate Governance" section.

Stockholder Communications with the Board of Directors

      SIGA  stockholders may send  communications to the Board, any committee of
the Board or an individual director.  The process for so communicating is posted
on SIGA's website at www.siga.com under the "Corporate Governance" section.


                                       8


                          REPORT OF THE AUDIT COMMITTEE

      The members of the Audit  Committee  have been  appointed  by the Board of
Directors.  During the 2005 fiscal year, the Audit Committee consisted solely of
independent  directors,  as defined in Rule  4200(a)(15) of the NASD Marketplace
Rules. The Audit Committee operates under a written charter that was amended and
restated by the Board of  Directors  in March 2004 in order to assure  continued
compliance by SIGA with SEC and NASDAQ rules enacted in response to requirements
of the Sarbanes-Oxley Act.

      The Audit  Committee  assists the Board of  Directors  in  monitoring  the
integrity of SIGA's  financial  statements,  the independent  registered  public
accounting  firm's  qualifications  and  independence,  the  performance  of the
independent  registered  public accounting firm, and the compliance by SIGA with
legal and regulatory requirements. Management is responsible for SIGA's internal
controls and the financial reporting process. The independent  registered public
accounting  firm is responsible  for  performing an independent  audit of SIGA's
financial  statements in accordance with generally  accepted auditing  standards
and for  issuing a report on those  financial  statements.  The Audit  Committee
monitors and oversees these processes.

      In this  context,  the Audit  Committee  has  reviewed and  discussed  the
audited  financial  statements  for  the  year  ended  December  31,  2005  with
management and with  PricewaterhouseCoopers  LLP, SIGA's independent  registered
public    accounting    firm.   The   Audit   Committee   has   discussed   with
PricewaterhouseCoopers  LLP the matters required to be discussed by Statement on
Auditing  Standards  No.  61  (Communications  with  Audit  Committees),   which
includes,  among  other  items,  matters  related to the conduct of the audit of
SIGA's annual financial statements.

      The Audit  Committee  has also  received the written  disclosures  and the
letter from  PricewaterhouseCoopers LLP required by Independence Standards Board
Standard  No.  1  (Independence  Discussions  with  Audit  Committees)  and  has
discussed with  PricewaterhouseCoopers  LLP the issue of their independence from
SIGA and management. In addition, the Audit Committee has considered whether the
provision of non-audit services by the independent  registered public accounting
firm in 2005 is compatible with  maintaining the auditors'  independence and has
concluded that it is.

      Based on its review of the audited  financial  statements  and the various
discussions  noted  above,  the  Audit  Committee  recommended  to the  Board of
Directors  that the audited  financial  statements  be included in SIGA's Annual
Report on Form 10-K for the year ended  December 31, 2005.  The Audit  Committee
has also  recommended,  subject to  stockholder  ratification,  the selection of
SIGA's  independent  registered  public  accounting  firm  for the  year  ending
December 31, 2006.

      The members of the Audit Committee are Paul G. Savas,  Judy S. Slotkin and
James J.  Antal,  none of whom is or,  during the  fiscal  year  2005,  was,  an
employee of SIGA.

                              Respectfully submitted by the Audit Committee,
                              Paul G. Savas, Chairman
                              James J. Antal
                              Judy S. Slotkin


                                       9


             COMPENSATION COMMITTEE REPORT ON EXECUTIVE COMPENSATION

      During the year ended  December 31, 2005, the  Compensation  Committee was
comprised of Donald G. Drapkin, Paul G. Savas and Mehmet C. Oz. The Compensation
Committee's  duties  include  determination  of the Company's  compensation  and
benefit  policies  and  practices  for  executive  officers  and key  managerial
employees.  In  accordance  with rules  established  by the SEC,  the Company is
required to provide certain data and  information in regard to the  compensation
provided to the Company's Chief Executive Officer and the four other most highly
compensated executive officers.

      Compensation Policies

      The  overall  objectives  of the  Company's  compensation  program  are to
attract  and  retain the best  possible  executive  talent,  to  motivate  these
executives to achieve the goals inherent in the Company's business strategy,  to
maximize the link between  executive and stockholder  interests  through a stock
option  plan  and to  recognize  individual  contributions  as well  as  overall
business  results.  To achieve  these  objectives,  the Company has developed an
overall  compensation  strategy  and  specific  compensation  plans  that  tie a
substantial portion of an executive's compensation to performance.

      The key elements of the Company's  compensation  program  consist of fixed
compensation  in the form of base salary,  and the  discretion to award variable
compensation  in the forms of annual  incentive  compensation  and stock  option
awards.  The  Compensation  Committee's  policies  with respect to each of these
elements are discussed  below.  In addition,  while the elements of compensation
described below are considered separately, the Compensation Committee takes into
account the full compensation package afforded by the Company to the individual,
including  pension  benefits,  insurance  and  other  benefits,  as  well as the
programs described below.

      Base Salaries

      Base  salaries  for  executive  officers  are  determined  based  upon the
Compensation Committee's evaluation of the responsibilities of the position held
and the experience of the individual,  and by reference to historical  levels of
salary paid by the Company.

      Salary  adjustments are based on a periodic  evaluation of the performance
of the Company and each executive  officer,  as well as financial results of the
business.  The  Compensation  Committee  takes  into  account  the effect of any
corporate  transactions that have been consummated during the relevant year and,
where appropriate,  also considers  non-financial  performance  measures.  These
include the Company's market share,  scientific developments and improvements in
relations with employees.

      Annual Incentive Compensation Awards

      Annual   incentive   compensation  is  payable   pursuant  to  contractual
provisions  with  certain  executives  which  provide   eligibility  to  receive
performance  based bonuses and/or  discretionary  bonuses.  The annual incentive
compensation earned by the executives with respect to 2005 was discretionary and
determined by the Compensation Committee.

      Other Incentive Compensation Awards

      The principal component of executive compensation is the granting of stock
options,  which are  intended as a tool to  attract,  provide  incentive  to and
retain those executives who make the greatest contribution to the business,  and
who can have the greatest effect on the Company's long-term  profitability.  The
exercise  price of stock  options is set at a price equal to the market price of
the Common Stock at the time of the grant. The options therefore do not have any
value to the executive unless the market price of the Common Stock rises.

      Chief Executive Officer Compensation

      Dr.  Kasten began service as Chief  Executive  Officer on July 2, 2004 and
resigned his position  effective April 30, 2006. The  compensation of Dr. Kasten
had been governed by the terms of his Employment  Agreement  dated as of July 2,
2004,  which terms were modified as of his  resignation,  all as described below
under the heading "Employment Contracts."


                                       10


      Tax Deductibility Of Executive Compensation

      The  Compensation  Committee  attempts  to ensure  full  deductibility  of
compensation  notwithstanding  the  limitation on the  deductibility  of certain
compensation  in excess  of one  million  dollars  under  Section  162(m) of the
Internal  Revenue Code of 1986,  as amended (the "Code").  The  Company's  stock
options  are  designed so as to cause stock  options and bonuses  granted  there
under to be exempt from the limitations contained in Section 162(m) of the Code.

                         Respectfully submitted by the Compensation Committee,
                         Donald G. Drapkin
                         Paul G. Savas
                         Mehmet C. Oz


                                       11


                            COMMON STOCK PERFORMANCE

      The following line graph compares the cumulative total stockholder  return
through December 31, 2005,  assuming  reinvestment of dividends,  by an investor
who invested $100 on December 31, 2000 in each of (i) the Common Stock, (ii) the
NASDAQ National Market-US; and (iii) the NASDAQ Pharmaceutical Index.

                              [LINE CHART OMITTED]

Value of Initial Investment 12/31/00 12/31/01 12/31/02 12/31/03 12/31/04 12/31/05 - -------------------------------- ---------- ---------- ---------- ---------- ---------- ---------- SIGA Technologies, Inc. $ 100.00 $ 91.77 $ 45.25 $ 72.47 $ 52.53 $ 30.06 NASDAQ Composite Index $ 100.00 $ 83.80 $ 45.81 $ 66.77 $ 70.86 $ 72.87 NASDAQ Biotech Composite Index $ 100.00 $ 78.95 $ 54.06 $ 81.09 $ 88.06 $ 89.27
12 MANAGEMENT Officers The following table sets forth certain information with respect to the executive officers of SIGA:
Name Age Position ---- --- -------- Bernard L. Kasten Jr. M.D. (1) 60 Director, Chief Executive Officer Thomas N. Konatich (2) 60 Vice President, Chief Financial Officer, Secretary and Treasurer Dennis E. Hruby, Ph.D. 54 Vice President, Chief Scientific Officer John R. Odden (3) 52 Vice President - Business Development
(1) Dr. Kasten became Chief Executive Officer in the third quarter of 2004. Dr. Kasten resigned as Chief Executive Officer of SIGA effective as of April 30, 2006. (2) Mr. Konatich was appointed to serve in an additional capacity as Acting Chief Executive Officer effective as of May 1, 2006. (3) Mr. Odden became Vice President -- Business Development in the third quarter of 2004. He resigned as Vice President Business Development in September, 2005. Bernard L. Kasten, Jr., M.D. has been a director of SIGA since May 23, 2003 and was Chief Executive Officer from the third quarter of 2004 through April 30, 2006. Prior to becoming Chief Executive Officer of SIGA and since February 2002, Dr. Kasten has been Vice President, Medical Affairs of medPlus Inc., a healthcare information technology company and a wholly-owned subsidiary of Quest Diagnostics, Inc., a diagnostic testing, information and services company. Since 1975, Dr. Kasten has been a Diplomat of the American Board of Pathology with a sub-specialty certification 1976 in Medical Microbiology. Dr. Kasten's staff appointments have included service in the Division of Laboratory Services at The Cleveland Clinic; Associate of Pathology and Laboratory Services at the Bethesda Hospital Systems in Cincinnati, Ohio and Chief Laboratory Officer at Quest Diagnostics Incorporated. Dr. Kasten was a founder of Plexus Vaccine Inc., a vaccine company of which SIGA acquired substantially all of the assets in May 2003. Dr. Kasten is also a director of Seracare Life Sciences, Inc. Dr. Kasten is an author of "Infectious Disease Handbook" 5th Edition, 2003, Lexi-Comp Inc. Thomas N. Konatich has served as Vice President, Chief Financial Officer and Treasurer since April 1, 1998. He was named Secretary of SIGA on June 29, 2001 and from October 5, 2001 until July 2, 2004 was our Acting Chief Executive Officer. Mr. Konatich resumed the position of Acting Chief Executive Officer on May 1, 2006. From November 1996 through March 1998, Mr. Konatich served as Chief Financial Officer and a director of Innapharma, Inc., a privately held pharmaceutical development company. From 1993 through November 1996, Mr. Konatich served as Vice President and Chief Financial Officer of Seragen, Inc., a publicly traded biopharmaceutical development company. Mr. Konatich has an MBA from the Columbia Graduate School of Business. Dennis E. Hruby, Ph.D. has served as Vice President - Chief Scientific Officer since June 2000. From April 1, 1997 through June 2000, Dr. Hruby was our Vice President of Research. From January 1996 through March 1997, Dr. Hruby served as a senior scientific advisor to SIGA. Dr. Hruby is a Professor of Microbiology at Oregon State University, and from 1990 to 1993 was Director of the Molecular and Cellular Biology Program and Associate Director of the Center for Gene Research and Biotechnology. Dr. Hruby specializes in virology and cell biology research, and the use of viral and bacterial vectors to produce recombinant vaccines. He is a member of the American Society of Virology, the American Society for Microbiology and a fellow of the American Academy of Microbiology. Dr. Hruby received a Ph.D. in microbiology from the University of Colorado Medical Center and a B.S. in microbiology from Oregon State University. John R. Odden had served as Vice President -- Business Development of SIGA from the third quarter of 2004 until September, 2005. From October 2002 until he became Vice President -- Business Development of SIGA in the third quarter of 2004, he was Vice President, Business Development for Quest Diagnostics, Inc. and its MedPlus, Inc. division, the nation's leading provider of diagnostics testing, information and services, where he was responsible for launching a national biosurveillance solution for homeland security and managing relationships with 13 major healthcare information technology companies. From 1996 through October 2002, he held a series of progressive leadership roles at First Consulting Group, a leading provider of consulting and systems integration services for life sciences, healthcare and government health services businesses. Mr. Odden has a B.S. in mathematics from the California Institute of Technology. Summary Compensation Table The following table sets forth the total compensation paid or accrued for the years ended December 31, 2005, 2004 and 2003, for each person who acted as SIGA's Chief Executive Officer at any time during the year ended December 31, 2005, and its most highly compensated executive officers, other than its Chief Executive Officer, whose salary and bonus for the fiscal year ended December 31, 2005 were in excess of $100,000 each. Summary Compensation Table
Long-Term Compensation Securities Other Annual Underlying Name and Principal Position Year Salary ($) Comensation ($) Bonus ($) Options (#) - --------------------------- ------- ------------ ----------------- ----------- --------------- Bernard L. Kasten, M.D. 2005 250,000 -- -- -- Chief Executive Officer (1) 2004 113,636 -- -- 2,500,000 2003 -- -- -- -- Thomas N. Konatich 2005 230,000 -- 35,000 -- Chief Financial Officer (2) 2004 218,485 -- 50,000 150,000 2003 210,000 -- -- -- Dennis E. Hruby, Ph.D. 2005 225,000 -- 112,500 -- Chief Scientific Officer 2004 213,363 -- 63,000 150,000 2003 210,000 -- -- --
(1) Dr. Kasten became Chief Executive Officer in the third quarter of 2004. His annual salary was $250,000. Dr. Kasten resigned as Chief Executive Officer of SIGA effective as of April 30, 2006. (2) Mr. Konatich was appointed to serve in an additional capacity as Acting Chief Executive Officer effective as of May 1, 2006. Option Grants for the Year Ended December 31, 2005 No options were granted during the year ended December 31, 2005 to anyone who served as Chief Executive Officer and its three highest paid employees. 14 Option Exercises in Last Fiscal Year and Fiscal Year-End Option Values The following table provides certain summary information concerning stock options held as of December 31, 2005 by SIGA's Chief Executive Officer and its three most highly compensated executive officers, other than its Chief Executive Officer. No options were exercised during fiscal 2005 by any of the officers.
Value of Unexercised Number of Securities Underlying In-The-Money Options Unexercised Options # At fiscal Year-End ($) (1) --------------------- -------------------------- Exercisable Unexercisable Exercisable Unexercisable ----------- ------------- ----------- ------------- Bernard L. Kasten, M.D. 933,332 1,666,668 -- -- Thomas N. Konatich 545,000 -- -- -- Dennis E. Hruby, Ph.D. 550,000 75,000 -- --
(1) Based upon the closing price on December 31, 2005, as reported on the Nasdaq SmallCap Market and the exercise price per option. Long-Term Incentive Plans--Awards in Last Fiscal Year As of January 1, 1996, we adopted our 1996 Incentive and Non-Qualified Stock Option Plan. An amendment and restatement of such plan, as amended, was adopted on May 3, 2001 and was further refined by the Board of Directors on June 29, 2001 (the "Plan"). The Plan was approved by our stockholders at an annual meeting on August 15, 2001, and amended on January 8, 2004, to increase the maximum number of shares of common stock available for issuance under the Plan to 10,000,000. Stock options may be granted to key employees, consultants and outside directors pursuant to the Plan. The Plan was amended again at our annual meeting on May 26, 2005, when our stockholders voted to increase the maximum number of shares of common stock available for issuance under the Plan from 10,000,000 to 11,000,000. The Plan is administered by our Compensation Committee which determines persons to be granted stock options, the amount of stock options to be granted to each such person, and the terms and conditions of any stock options as permitted under the Plan. The members of the Compensation Committee are Mehmet C. Oz, M.D., Paul G. Savas and Donald G. Drapkin. See "Committees of the Board of Directors" above for more information. Both Incentive Options and Nonqualified Options may be granted under the Plan. An Incentive Option is intended to qualify as an incentive stock option within the meaning of Section 422 of the Internal Revenue Code of 1986, as amended (the "Code"). Any Incentive Option granted under the Plan will have an exercise price of not less than 100% of the fair market value of the shares on the date on which such option is granted. With respect to an Incentive Option granted to an employee who owns more than 10% of the total combined voting stock of SIGA or of any parent or subsidiary of SIGA, the exercise price for such option must be at least 110% of the fair market value of the shares subject to the option on the date the option is granted. The Plan, as amended, provides for the granting of options to purchase 11,000,000 shares of common stock, of which 9,399,561 options were outstanding as of December 31, 2005. 15 During the fiscal year ending December 31, 2005, the named Directors and Officers of SIGA received long-term incentive compensation under the Plan as shown in the following table.
(a) (b) (c) (d) (e) (f) --- --- --- --- --- --- Estimated Future Payouts Under Number of Performance or Non-Stock Price Based Plans Shares, Units or Other Period Until --------------------------- Other Rights Maturation of Threshold Target Maximum Name (#) Payout ($ or #) ($ or #) ($ or #) - ---- --- ------ -------- -------- -------- Donald G. Drapkin 10,000 6/2/2015 N/A N/A N/A James J. Antal 10,000 6/2/2015 N/A N/A N/A Thomas E. Constance 10,000 6/2/2015 N/A N/A N/A Adnan M. Mjalli, Ph.D. 10,000 6/2/2015 N/A N/A N/A Mehmet C. Oz, M.D. 10,000 6/2/2015 N/A N/A N/A Eric A. Rose, M.D. 10,000 6/2/2015 N/A N/A N/A Paul G. Savas 10,000 6/2/2015 N/A N/A N/A Judy S. Slotkin 10,000 6/2/2015 N/A N/A N/A Michael Weiner, M.D. 10,000 6/2/2015 N/A N/A N/A
Employment Contracts and Directors Compensation Directors' Compensation Directors who are not currently receiving compensation as officers or employees of the Company or any of its affiliates receive $1,000 per meeting for board meetings and will be reimbursed for expenses incurred by them in connection with serving on our Board of Directors. The chairman of the Audit Committee will receive $1,000 per meeting for meetings of the Audit Committee and all other members of the Audit Committee will receive $500 per meeting for meetings of the Audit Committee. Members of Compensation Committee and Nominating and Corporate Governance Committee will receive $500 per meeting for meetings of the Compensation Committee and Nominating and Corporate Governance Committee. Non-employee directors will receive an initial grant of 25,000 options, upon such non-employee director's first election to the Board of Directors, which such options will be granted under SIGA's Amended and Restated 1996 Incentive and Non-Qualified Stock Option Plan. In addition, non-employee directors will receive an annual grant of 10,000 options under SIGA's Amended and Restated 1996 Incentive and Non-Qualified Stock Option Plan, made at each Annual Meeting and commencing with the 2005 Annual Meeting. All such options have an exercise price equal to the fair market value of the underlying SIGA shares on the date of grant. 16 Equity Compensation Plan Information The following table sets forth certain compensation plan information with respect to both equity compensation plans approved by security holders and equity compensation plans not approved by security holders as of December 31, 2005:
Number of securities remaining available for Number of securities future issuance under to be issued upon Weighted-average equity compensation exercise of exercise price of plans (excluding outstanding options, outstanding options, securities reflected in Plan Category warrants and rights warrants and rights column (a)) (a) (b) (c) Equity compensation plans approved by security holders (1) 9,399,561 $2.00 1,385,398 Equity compensation plans not approved by security holders 250,000 $2.00 -- Total 9,649,561 $2.00 1,385,398
(1) SIGA Technologies, inc., Amended and Restated 1996 Incentive and Non-Qualified Stock Option Plan. Employment Contracts Dr. Bernard L. Kasten, SIGA's Chief Executive Officer, was employed by SIGA under an employment agreement dated July 2, 2004. Dr. Kasten received an annual base salary of $250,000 and his employment agreement also provided for additional bonus payments at the discretion of the Board of Directors. On July 2, 2004, he received options to purchase 2,500,000 shares of common stock with an exercise price of $1.30 per share, of which 500,000 shares vested on the date of grant; with respect to the next 1,000,000 shares, an additional 166,666 shares vested on the end of each six (6) month period after date of grant until the end of the sixth six (6) month period at which time 166,667 shares were to vest. Effective April 30, 2006, SIGA and Dr. Kasten reached an agreement for Dr. Kasten's resignation. In connection with such agreed upon resignation, SIGA and Dr. Kasten entered into a Separation Agreement dated March 31, 2006 (the "Separation Agreement"). Under the provisions of the Separation Agreement, Dr. Kasten received his salary on the existing terms and conditions as set forth in his Employment Agreement with SIGA, dated July 2, 2004 (the "Employment Agreement") in lieu of any other severance or payment, through September 16, 2006 (the "Separation Period"). Concurrently with the execution of the Separation Agreement, SIGA and Dr. Kasten also amended Dr. Kasten's Incentive Stock Option Agreement such that Dr. Kasten's "Milestone Options" (as such term is defined in the Employment Agreement) were cancelled and Dr. Kasten's "Time Vested Options" (as such term is defined in the Employment Agreement) were amended such that with respect to the Time Vested Options which have not vested as of the date of the Separation Agreement, such options will vest as follows: with respect to 166,666 shares as of July 2, 2006 and with respect to the remaining 83,334 shares, as of January 2, 2007. Time Vested Options granted to Dr. Kasten which have vested prior to the date of the Separation Agreement shall remain unchanged. Dr. Kasten will also be permitted to continue to receive medical and/or dental insurance benefits under the relevant SIGA plans until (i) the end of the Remaining Tenure (defined as the earlier of April 30, 2006 or Dr. Kasten's obtaining new employment), (ii) he becomes entitled to Medicare or (iii) he becomes eligible for coverage under medical and/or dental insurance benefit plans, as the case may be, of another employer through his future employment, whichever occurs first. The Separation Agreement also contains mutual non-disparagement and release terms, requires that Dr. Kasten remain available to SIGA on a reasonable basis for transitional purposes during the Separation Period and requires SIGA to indemnify Dr. Kasten under the terms of its certificate of incorporation and bylaws for acts relating to his employment. 17 Thomas N. Konatich, SIGA's Acting Chief Executive Officer, Vice President, Chief Financial Officer, Secretary and Treasurer, is employed by SIGA under an employment agreement dated April 1, 1998, as amended on January 19, 2000, as amended and restated on October 6, 2000, as amended as of January 31, 2002, as amended on November 5, 2002, as amended on July 29, 2004 and as amended on February 1, 2006. This employment agreement expires on June 30, 2007. Mr. Konatich has previously also served as SIGA's Acting Chief Executive Officer, which duties concluded on July 2, 2004. Mr. Konatich receives an annual base salary of $230,000 and received a one-time payment of $50,000 for his initial service as Acting Chief Executive Officer. His employment agreement also provides for an additional bonus payment at the discretion of the Board of Directors and not to exceed 25% of his annual base salary amount. He received options to purchase 95,000 shares of common stock, at $4.44 on April 1, 1998. The options vested on a pro rata basis on the first, second, third and fourth anniversaries of the agreement. On January 19, 2000, he received an additional grant to purchase 100,000 shares at an exercise price of $2.00 per share. These options vest on a pro rata basis each quarter through January 19, 2002. On January 31, 2002, Mr. Konatich was granted an "Incentive Stock Option" to purchase 50,000 shares at an exercise price of $3.94 per share. Such options vest in eight equal quarterly installments beginning on April 20, 2002. On November 5, 2002, Mr. Konatich was granted an Incentive Stock Option to purchase 150,000 shares at an exercise price of $2.50 per share. 75,000 of these options vested immediately and 75,000 options vested on September 1, 2003. On July 29, 2004, Mr. Konatich was granted an Incentive Stock Option to purchase 150,000 shares at an exercise price of $1.40 per share. 75,000 of these options vested immediately and with the remaining 75,000 options vesting on a pro rata basis from January 1, 2005 through December 31, 2005 with no provision for acceleration under any circumstances. Mr. Konatich is also eligible to receive additional stock options and bonuses at the discretion of the Board of Directors. SIGA may terminate the employment agreement with or without cause (as such term is defined in the employment agreement), provided that upon any termination without cause, SIGA will be obligated to continue to pay Mr. Konatich's salary and all other amounts due under the employment agreement for the remainder of the term. If Mr. Konatich is terminated due to a change of control (as such term is defined in the employment agreement), SIGA is required to pay Mr. Konatich a change in control amount (as such term is defined in the employment agreement) plus his accrued and unpaid base salary, and, upon the first event constituting a change of control, all stock options and other stock-based grants to Mr. Konatich shall immediately and irrevocably vest and become exercisable upon the date of such event. Dr. Dennis E. Hruby, Chief Scientific Officer, is employed by SIGA under an employment agreement dated January 1, 1998, as amended on June 16, 2000, as amended on January 31, 2002, as amended on October 3, 2002 and as amended on July 29, 2004. This employment agreement expires on December 31, 2007. Dr. Hruby receives a base salary of $225,000 per year and his employment agreement also provides for additional bonus payments at the discretion of the Board of Directors and not to exceed 50% of his base salary amount. Dr. Hruby received options to purchase 10,000 shares of common stock at an exercise price of $5.00 per share on April 1, 1997 and 40,000 shares of common stock at an exercise price of $4.63 per share on April 1, 1998. The options became exercisable on a pro rata basis on the first, second, third and fourth anniversaries of the agreement. Under the June 16, 2000 amendment, Dr. Hruby was granted options to purchase 125,000 shares of SIGA's common stock at $2.00 per share. The options vest ratably over the remaining term of the amendment. The January 31, 2002 amendment changed the terms of the lock-up agreed to in the June 16, 2000 amendment to the employment agreement limiting Hruby's ability to sell SIGA stock. On January 31, 2002, Dr. Hruby was granted an "Incentive Stock Option" to purchase 50,000 shares at an exercise price of $3.94 per share. Such options vest in four equal annual installments beginning on August 15, 2002. As part of the October 3, 2002 amendment, Dr. Hruby was granted an option to purchase 300,000 shares of common stock. Options with respect to 75,000 shares vested upon the signing of the amendment and an additional 75,000 shares shall vest on a pro rata basis on September 1 of each 2003, 2004 and 2005. The options have an exercise price of $2.50 per share. Dr. Hruby surrendered his option to purchase up to 50,000 shares of common stock of SIGA at an exercise price of $3.94 that he was granted under an earlier amendment. On July 29, 2004, Dr. Hruby was granted an Incentive Stock Option to purchase 150,000 shares at an exercise price of $1.40 per share, which options shall vest in 75,000 share increments on December 31 of each year, commencing December 31, 2005. Dr. Hruby is eligible to receive additional stock options and bonuses at the discretion of the Board of Directors. SIGA may terminate the employment agreement with or without cause (as such term is defined in the employment agreement), provided that upon any termination without cause SIGA will be obligated to continue to pay Dr. Hruby's salary for the remainder of the term. In addition, SIGA shall have the right 18 to terminate Dr. Hruby's employment upon one (1) year written notice with such termination being treated as a termination for cause. If Dr. Hruby is terminated due to a change of control (as such term is defined in the employment agreement), SIGA shall pay Dr. Hruby a change in control amount (as such term is defined in the employment agreement) plus his accrued and unpaid base salary, and, upon the first event constituting a change of control, all stock options and other stock-based grants to Dr. Hruby shall immediately and irrevocably vest and become exercisable upon the date of such event. 19 SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT The following tables set forth certain information regarding the beneficial ownership of SIGA's voting securities as of October 31, 2006 of (i) each person known to SIGA to beneficially own more than 5% of the applicable class of voting securities, (ii) each director and director nominee of SIGA, (iii) each Named Officer and (iv) all directors and executive officers of SIGA as a group. As of November 6, 2006, a total of 31,796,454 shares of Common Stock were outstanding. Each share of Common Stock is entitled to one vote on matters on which holders of Common Stock are eligible to vote. The column entitled "Percentage of Total Voting Stock Outstanding" shows the percentage of total voting stock beneficially owned by each listed party. The number of shares beneficially owned is determined under rules promulgated by the Securities and Exchange Commission, and the information is not necessarily indicative of beneficial ownership for any other purpose. Under those rules, beneficial ownership includes any shares as to which the individual has sole or shared voting power or investment power and also any shares which the individual has the right to acquire within 60 days of October 31, 2006, through the exercise or conversion of any stock option, convertible security, warrant or other right. Unless otherwise indicated, each person or entity named in the table has sole voting power and investment power (or shares that power with that person's spouse) with respect to all shares of capital stock listed as owned by that person or entity. Ownership of Common Stock The following tables set forth certain information regarding the beneficial ownership of SIGA's voting securities as of October 31, 2006 of (i) each person known to SIGA to beneficially own more than 5% of the applicable class of voting securities, (ii) each director and director nominee of SIGA, (iii) each Named Officer, and (iv) all directors and officers of SIGA as a group. As of November 6, 2006, a total of 31,796,454 shares of common stock were outstanding. Each share of common stock is entitled to one vote on matters on which common stockholders are eligible to vote. The column entitled "Percentage of Total Voting Stock" shows the percentage of total voting stock beneficially owned by each listed party.
Percentage of Percentage of Name and Address of Amount of Beneficial Common Stock Total Voting Beneficial Owner (1) Ownership (2) Outstanding Stock Outstanding - -------------------- ---------------------- ------------------- --------------------- Beneficial Holders MacAndrews & Forbes Inc. (3) 35 East 62nd Street New York, NY 10021 ................................ 5,620,771(4) 16.8% 16.8% Eliot Rose Asset Management, LLC 10 Weybosset Street Suite 401 Providence, RI 02903 .............................. 3,216,500 10.1% 10.1% TransTech Pharma, Inc. 4170 Mendenhall Oaks Parkway High Point, NC 27265 .............................. 5,296,634(5) 15.8% 15.8% Officers and Directors Donald G. Drapkin (6) 35 East 62nd Street New York, NY 10021 ................................ 1,808,326(7) 5.4% 5.4% James J. Antal 30952 Steeplechase Dr. San Juan Capistrano, CA 94704 ..................... 46,154(8) * * Judy S. Slotkin (19) 888 Park Avenue NY, NY 10021 ...................................... 35,000(9) * *
20
Percentage of Percentage of Name and Address of Amount of Beneficial Common Stock Total Voting Beneficial Owner (1) Ownership (2) Outstanding Stock Outstanding - -------------------- ---------------------- ------------------- --------------------- Thomas E. Constance 1177 Avenue of the Americas, New York, NY 10036 ................................ 263,467(10) * * Bernard L. Kasten Jr., M.D.(11) ................... 1,712,360(12) 5.2% 5.2% Adnan M. Mjalli, Ph.D 4170 Mendenhall Oaks Parkway, Suite 110 High Point, NC 27265 .............................. 35,000(13) * -- Mehmet C. Oz, M.D. 177 Fort Washington Ave New York, NY 10032 ................................ 135,000(14) * * Eric A. Rose, M.D. (15) 122 East 78th Street New York, NY 10021 ................................ 800,090(16) 2.5% 2.5% Paul G. Savas 35 East 62nd Street New York, NY 10021 ................................ 61,664(17) * * Michael A. Weiner, M.D. 161 Fort Washington Ave. New York, NY 10032 ................................ 122,500(14) * * Thomas N. Konatich ................................ 545,000(18) 1.7% 1.7% Dennis E. Hruby, Ph.D. ............................ 550,000(18) 1.7% 1.7% All Executive Officers and Directors as a group (thirteen persons) .......................... 6,114,561(20) 16.5% 16.5%
- ---------- * Less than 1% (1) Unless otherwise indicated the address of each beneficial owner identified is 420 Lexington Avenue, Suite 408, New York, NY 10170. (2) Unless otherwise indicated, each person has sole investment and voting power with respect to the shares indicated. For purposes of this table, a person or group of persons is deemed to have "beneficial ownership" of any shares as of a given date which such person has the right to acquire within 60 days after such date. For purposes of computing the percentage of outstanding shares held by each person or group of persons named above on a given date, any security which such person or persons has the right to acquire within 60 days after such date is deemed to be outstanding for the purpose of computing the percentage ownership of such person or persons, but is not deemed to be outstanding for the purpose of computing the percentage ownership of any other person. (3) MacAndrews & Forbes Inc. is a direct wholly-owned subsidiary of MacAndrews & Forbes Holdings Inc., a holding company whose sole stockholder is Ronald O. Perelman. (4) Includes 1,764,206 shares of common stock issuable upon exercise of warrants. (5) Includes 1,824,412 shares of common stock issuable upon exercise of warrants. (6) Mr. Drapkin is a director and Vice Chairman of MacAndrews & Forbes Holdings Inc. and MacAndrews & Forbes Inc. and a director of TransTech Pharma. 21 (7) Includes 1,135,000 shares of common stock issuable upon exercise of options, shares of common stock underlying a warrant to purchase up to 347,826 shares of common stock and shares of common stock underlying a warrant to purchase up to 30,500 shares of common stock (the "Drapkin September 2001 Investor Warrant"). However, the Drapkin September 2001 Investor Warrant provides that, with certain limited exceptions, such warrant is not exercisable if, as a result of such exercise, the number of shares of common stock beneficially owned by Mr. Drapkin and his affiliates (other than shares of common stock which may be deemed beneficially owned through the ownership of the unexercised portion of the Drapkin September 2001 Investor Warrant) would exceed 9.99% of the outstanding shares of common stock. Does not include shares of common stock that Mr. Drapkin, as a director and Vice Chairman of Mafco Holdings Inc. and MacAndrews & Forbes or as director of TransTech Pharma, may be deemed to beneficially own and as to which Mr. Drapkin disclaims beneficial ownership. (8) Includes 35,000 shares of common stock issuable upon exercise of options. (9) Includes 35,000 shares of common stock issuable upon exercise of options. (10) Includes 12,200 shares issuable upon exercise of warrants and 235,000 shares of common stock issuable upon exercise of options. (11) Dr. Kasten became our Chief Executive Officer in the third quarter of 2004. Dr. Kasten resigned as Chief Executive Officer of SIGA effective as of April 30, 2006. (12) Includes 1,350 shares of common stock issuable upon exercise of warrants and 1,350,000 shares of common stock issuable upon exercise of options. (13) Includes 35,000 shares of common stock issuable upon exercise of options. Does not include shares of common stock that Dr. Mjalli, as a director of TransTech Pharma, may be deemed to beneficially own and as to which Dr. Mjalli disclaims beneficial ownership. (14) Includes 12,500 shares issuable upon exercise of warrants and 110,000 shares issuable upon exercise of options. (15) Dr. Rose is a director of TransTech Pharma. (16) Includes 88,610 shares of common stock issuable upon exercise of warrants and 610,000 shares of common stock issuable upon exercise of options. Does not include shares of common stock that Dr. Rose, as a director of TransTech Pharma, may be deemed to beneficially own and as to which Dr. Rose disclaims beneficial ownership. (17) Includes 9,303 shares of common stock issuable upon exercise of warrants and 35,000 shares issuable upon exercise of options. (18) Neither of Messrs. Konatich and Hruby own shares of common stock. All shares listed as beneficially owned by each of Messrs. Konatich and Hruby are shares issuable upon exercise of stock options. (19) Does not include 35,605 shares of common stock owned by Ms. Slotkin's spouse to which she disclaims beneficial ownership. (20) See footnotes (6)-(21). 22 CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS Thomas E. Constance, a director of SIGA, is Chairman of Kramer Levin Naftalis & Frankel LLP, a law firm in New York City, which SIGA has retained to provide legal services. Adnan M. Mjalli, a director of SIGA, is also President and Chief Executive Officer of TransTech Pharma. 23 PROPOSAL NO. 2 RATIFICATION OF APPOINTMENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM The Audit Committee of the Board of Directors has appointed the firm of PricewaterhouseCoopers LLP as SIGA's independent registered public accounting firm to audit the financial statements of SIGA for the fiscal year ending December 31, 2006, and recommends that stockholders vote for ratification of this appointment. PricewaterhouseCoopers LLP has audited SIGA's financial statements since January 1997. Representatives of PricewaterhouseCoopers LLP are expected to be present at the Annual Meeting and will have the opportunity to make a statement if they desire to do so, and are expected to be available to respond to appropriate questions. The affirmative vote of a majority of the total votes cast on such proposal in person or by proxy at the Annual Meeting will be required to ratify the selection of PricewaterhouseCoopers LLP. If the stockholders fail to ratify the selection, the Audit Committee will reconsider its selection of auditors. Even if the selection is ratified, the Audit Committee, in its discretion, may direct the appointment of a different independent registered public accounting firm at any time during the year, if it determines that such change would be in the best interests of SIGA and its stockholders. Audit Fees PricewaterhouseCoopers LLP billed SIGA $184,300 in the aggregate, for professional services rendered by them for the audit of SIGA's annual financial statements for the fiscal year ended December 31, 2005, reviews of the interim financial statements included in SIGA's Forms 10-Q filed during the year ended December 31, 2005 and consents and reviews of various documents filed with the SEC during the year ended December 31, 2005. PricewaterhouseCoopers LLP billed SIGA $213,300 in the aggregate, for professional services rendered by them for the audit of SIGA's annual financial statements for the fiscal year ended December 31, 2004, reviews of the interim financial statements included in SIGA's Forms 10-QSB filed during the year ended December 31, 2004 and consents and reviews of various documents filed with the SEC during the year ended December 31, 2004. Audit Related Fees There were no Audit Related Fees in 2005 and 2004. Tax Fees PricewaterhouseCoopers LLP did not render any professional services for tax compliance, tax advice or tax planning during either of the fiscal years ended December 31, 2005 or December 31, 2004. All Other Fees PricewaterhouseCoopers LLP did not provide any products or render any professional services (other than those covered above under "Audit Fees," "Audited Related Fees," and "Tax Fees") during either of the fiscal years ended December 31, 2005 or December 31, 2004. Policy on Audit Committee Pre-Approval of Audit and Permissible Non-Audit Services of Independent Registered Public Accounting Firm The Audit Committee's policy is to pre-approve all audit and permissible non-audit services provided by the independent registered public accounting firm. These services may include audit services, audit-related services, tax services, and other services. 24 SIGA did not make use in fiscal year 2005 of the rule that waives pre-approval requirements for non-audit services in certain cases if the fees for these services constitute less than 5% of the total fees paid to the auditor during the year. THE BOARD OF DIRECTORS RECOMMENDS THAT THE STOCKHOLDERS VOTE "FOR" THE RATIFICATION (ITEM 2 OF THE ENCLOSED PROXY CARD) OF THE APPOINTMENT OF PRICEWATERHOUSECOOPERS LLP AS SIGA'S INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM FOR THE FISCAL YEAR ENDING DECEMBER 31, 2006. 25
- ------------------------------------------------------------------------------------------------ New Plan Benefits (1) - ------------------------------------------------------------------------------------------------ Name and Position Additional Stock Options Granted Dollar Value ($) - ----------------- -------------------------------- ---------------- - ------------------------------------------------------------------------------------------------ Non-Executive Director Group 90,000 (2) 325,800 (3) - ------------------------------------------------------------------------------------------------
(1) All other future benefits under the Plan will be made at the discretion of SIGA's Compensation Committee and, accordingly, are not determinable at this time. (2) The option grants reflected in the table above will be made in accordance with SIGA's previously disclosed Director Compensation Program. (3) Current market price on the October 31, 2006. 26 STOCKHOLDER PROPOSALS Stockholder proposals to be presented at the 2007 Annual Meeting of Stockholders, for inclusion in SIGA's proxy statement and form of proxy relating to that meeting, must be received by SIGA at its offices in New York, New York, addressed to the Secretary, not later than January 1, 2007. Such proposals must comply with SIGA's By-Laws and the requirements of Regulation 14A of the Securities Exchange Act of 1934 (the "Exchange Act"). In addition, Rule 14a-4 of the Exchange Act governs SIGA's use of its discretionary proxy voting authority with respect to a stockholder proposal that is not addressed in the proxy statement. With respect to SIGA's 2007 Annual Meeting of Stockholders, if SIGA is not provided notice of a stockholder proposal prior to March 16, 2007, SIGA will be allowed to use its discretionary voting authority when the proposal is raised at the meeting, without any discussion of the matter in the proxy statement. SECTION 16 BENEFICIAL OWNERSHIP REPORTING COMPLIANCE Section 16(a) of the Exchange Act requires SIGA's officers and directors, and persons who own more than ten percent of a registered class of SIGA's equity securities, to file reports of ownership and changes in ownership with the Securities and Exchange Commission. Officers, directors and greater than ten-percent stockholders are required by Securities and Exchange Commission regulation to furnish SIGA with copies of all Section 16(a) reports that they file. Based solely upon review of the copies of such reports furnished to SIGA and written representations from certain of SIGA's executive officers and directors that no other such reports were required, SIGA believes that during the fiscal year ended December 31, 2005, no individuals failed to file reports relating to any transaction as required by Section 16 of the Exchange Act. AVAILABILITY OF ANNUAL REPORT AND FORM 10-K TO STOCKHOLDERS SIGA's Annual Report to Stockholders for the year ended December 31, 2005 accompanies this proxy statement. SIGA will provide to any stockholder, upon written request and without charge, a copy of its most recent Report on Form 10-K, including the financial statements, as filed with the Securities and Exchange Commission. All requests for such reports should be directed to the Chief Financial Officer, 420 Lexington Avenue, Suite 408, New York, New York 10170, telephone number (212) 672-9100. OTHER MATTERS At the date of this proxy statement, management was not aware that any matters not referred to in this proxy statement would be presented for action at the Annual Meeting. If any other matters should come before the Annual Meeting, the persons named in the accompanying proxy will have discretionary authority to vote all proxies in accordance with their best judgment, unless otherwise restricted by law. BY ORDER OF THE BOARD OF DIRECTORS /s/ Thomas N. Konatich ---------------------- Thomas N. Konatich Secretary Dated: November 17, 2006 27 SIGA TECHNOLOGIES, INC. PROXY SOLICITED BY THE BOARD OF DIRECTORS FOR THE ANNUAL MEETING OF STOCKHOLDERS TO BE HELD ON DECEMBER 19, 2006 The undersigned hereby appoints Thomas N. Konatich as attorney and proxy of the undersigned, with full power of substitution, to vote all of the shares of stock of SIGA Technologies, Inc. which the undersigned may be entitled to vote at the Annual Meeting of Stockholders of SIGA Technologies, Inc. to be held at the offices of Kramer Levin Naftalis & Frankel LLP, 1177 Avenue of the Americas, 29th floor, New York, New York 10036, on Tuesday, December 19, 2006, at 10:30 a.m. (local time), and at any and all postponements, continuations and adjournments thereof, with all powers that the undersigned would possess if personally present, upon and in respect of the following matters and in accordance with the following instructions, with discretionary authority as to any and all other matters that may properly come before the meeting. UNLESS A CONTRARY DIRECTION IS INDICATED, THIS PROXY WILL BE VOTED FOR ALL NOMINEES LISTED IN PROPOSAL NO. 1, AND FOR THE RATIFICATION OF PRICEWATERHOUSECOOPERS LLP AS THE INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM OF SIGA TECHNOLOGIES, INC. FOR THE FISCAL YEAR ENDING DECEMBER 31, 2006. AS MORE SPECIFICALLY DESCRIBED IN THE PROXY STATEMENT. IF SPECIFIC INSTRUCTIONS ARE INDICATED, THIS PROXY WILL BE VOTED IN ACCORDANCE THEREWITH. THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" THE DIRECTOR NOMINEES LISTED BELOW, AND "FOR" THE SELECTION OF PRICEWATERHOUSECOOPERS LLP AS THE INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM OF SIGA TECHNOLOGIES, INC. FOR THE FISCAL YEAR ENDING DECEMBER 31, 2006. PLEASE VOTE, SIGN, DATE AND RETURN PROMPTLY IN THE ENCLOSED ENVELOPE. PLEASE MARK YOUR VOTE IN BLUE OR BLACK INK AS SHOWN HERE: |X| 1. To elect ten directors. |_| FOR ALL NOMINEES |_| WITHHOLD AUTHORITY FOR ALL NOMINEES |_| FOR ALL EXCEPT (See instructions below) NOMINEES: o Donald G. Drapkin o Thomas E. Constance o Adnan M. Mjalli, Ph.D. o Mehmet C. Oz, M.D. o Eric A. Rose, M.D. o Paul G. Savas o Michael A. Weiner, M.D. o Judy S. Slotkin o James J. Antal o Scott M. Hammer, M.D. INSTRUCTION: To withhold authority to vote for any individual nominee(s), mark "FOR ALL EXCEPT" and fill in circle next to each nominee you wish to withhold, as shown here: |X| 2. To ratify the selection of PricewaterhouseCoopers LLP as the independent registered public accounting firm of SIGA Technologies, Inc. for the fiscal year ending December 31, 2005. |_| FOR |_| AGAINST |_| ABSTAIN THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS. IT MAY BE REVOKED PRIOR TO ITS EXERCISE. RECEIPT OF NOTICE OF THE ANNUAL MEETING AND PROXY STATEMENT IS HEREBY ACKNOWLEDGED, AND THE TERMS OF THE NOTICE AND PROXY STATEMENT ARE HEREBY INCORPORATED BY REFERENCE INTO THIS PROXY. THE UNDERSIGNED HEREBY REVOKES ALL PROXIES HERETOFORE GIVEN FOR SAID MEETING OR ANY AND ALL ADJOURNMENTS, POSTPONEMENTS AND CONTINUATIONS THEREOF. PLEASE VOTE, DATE, SIGN AND PROMPTLY RETURN THIS PROXY IN THE ENCLOSED RETURN ENVELOPE WHICH IS POSTAGE PREPAID IF MAILED IN THE UNITED STATES. - ----------------------------------------------------------------- To change the address on your account, please check the box at right and indicate your new address in the address space above. Please note that changes to the registered name(s) on the account may not be submitted via this method. |_| Signature of Stockholder:_______________________________________________________ Date:____________________ Signature of Stockholder:_______________________________________________________ Date:____________________ PLEASE SIGN EXACTLY AS YOUR NAME APPEARS ON THIS PROXY. WHERE SHARES ARE HELD JOINTLY, EACH HOLDER SHOULD SIGN. WHEN SIGNING AS EXECUTOR, ADMINISTRATOR, ATTORNEY-IN-FACT, TRUSTEE OR GUARDIAN, PLEASE GIVE FULL TITLE AS SUCH. IF SIGNER IS A CORPORATION, PLEASE SIGN IN FULL CORPORATE NAME BY DULY AUTHORIZED OFFICER, GIVING FULL TITLE AS SUCH. IF SIGNER IS A PARTNERSHIP, PLEASE SIGN IN FULL PARTNERSHIP NAME BY AUTHORIZED PERSON.